Inc.;President and Fellows of Harvard College;Dana-Farber Cancer Institute;Dana-Farber Cancer Institute, Inc.
发明人:
Tang, Weiping,Bradner, James Elliot,Schreiber, Stuart L.
申请号:
AU2009274549
公开号:
AU2009274549B2
申请日:
2009.07.22
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention provides novel compounds of formula (I) and pharmaceutical compositions thereof. The inventive compounds are useful as deacetylase inhibitors (e.g., histone deacetylase inhibitors) and may be useful in the treatment of proliferative diseases such as cancer. In particular, the inventive compounds are HDAC6 inhibitors. The invention also provide synthetic methods for preparing the inventive compounds.