An oral cannabinoid (CBD, CBDV, CBC, CBDA etc) formulation comprises one or more cannabinoids dissolved in a sovent system comprising water and a non-ionic surfactant such as poloxyethylene (2) sorbitan monooleate, polysorbate 80, macrogolglycerol hydrocystearate or a polyoxamer. The formulation of cannabidiol (CBD) in Kolliphor RH40 (also known as Cremophor RH 40, Macrogolglycerol hydroxystearate, PEG-40 castor oil, Polyoxyl 40 hydrogenated castor oil) is disclosed. Methods of mixing the formulation and of treatment of disorders amenable to cannabinoids are also disclosed.