The present invention is directed to monophasic pharmaceutical compositions comprising a conjugated estrogen and a hydrophilic or lipophilic excipient. The present invention is also directed to kits and applicators comprising the pharmaceutical compositions. The invention is also directed to methods for treating menopausal conditions in a female comprising administration of the pharmaceutical compositions.La présente invention concerne des compositions pharmaceutiques monophasiques comprenant un œstrogène conjugué et un excipient hydrophile ou lipophile. La présente invention concerne également des kits et des applicateurs comprenant lesdites compositions pharmaceutiques. Linvention concerne en outre des procédés de traitement de troubles liés à la ménopause chez la femme, comprenant ladministration des compositions pharmaceutiques.