Methods for reverting methylation by targeting DNMT3A and DNMT3B

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专利权人:

发明人:

申请号：

EP14170583.0

公开号：

EP2808398A1

申请日:

2008.07.30

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Methods for restoring a desired pattern of DNA methylation, inducing re-expression of methylation-silenced tumor suppressor genes (TSGs), and/or inhibiting tumorigenicity both in vitro and in vivo in a subject in need thereof by administering an effective amount of one or more miR-29s sufficient to target one or more of DNMT3A and DNMT3B are disclosed.

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