Tim Sparey,Andrew Ratcliffe,David Hallett,Edward Cochrane,Gilbert Lassalle,Alexandre Froidbise,Brett Stevenson
申请号:
US16606392
公开号:
US20200131208A1
申请日:
2018.04.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.