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Stable pharmaceutical compositions of saxagliptin or salts thereof
专利权人:
发明人:
Girish Kumar Jain,Venkataramana Naidu,Balasaheb Parshuram Wagh,Vijay Suggala
申请号:
US14436881
公开号:
US20150250734A1
申请日:
2013.05.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention refers to a stable pharmaceutical composition of saxagliptin or salts thereof. In particular, the invention relates to stable comprises a core and two or more layers coated on the core, wherein the composition or the inner first coat is free of polyvinyl alcohol. Such composition of saxagliptin may exhibit relatively improved storage stability and particularly, levels of degradants in the formulation during storage can be effectively controlled. The invention also includes a process of preparing such compositions and method of treating type-II diabetes mellitus by administering the composition to a patient in need thereof.
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