Stephen M. Condon,Matthew G. LaPorte,Yijun Deng,Susan R. Rippin
申请号:
US13926283
公开号:
US08802716B2
申请日:
2013.06.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPB (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less than 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposed are also disclosed.