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MELANOCORTIN RECEPTOR MODULATORS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF IN MEDICINAL AND COSMETIC PREPARATIONS FOR HUMAN USE
专利权人:
GALDERMA RESERCH END DEVELOPMENT
发明人:
BUI-PETER Kler (FR),БУИ-ПЕТЕР Клер (FR),SUZUKI Itaru (FR),СУЗУКИ Итару (FR),PELISSON Izabel (FR),ПЕЛИССОН Изабель (FR),KOLLETT Paskal (FR),КОЛЛЕТТ Паскаль (FR),TABE Samyuel (FR),ТАБЕ Самюэль (FR),LAFI,BUI-PETER KLER,БУИ-ПЕТЕР Клер,SUZUKI ITARU,СУЗУКИ Итару,PELISSON IZABEL,ПЕЛИССОН Изабель,KOLLETT PASKAL,КОЛЛЕТТ Паскаль,TABE SAMYUEL,ТАБЕ Самюэль,LAFITT GIJOM,ЛАФИТТ Гийом
申请号:
RU2011122635/04
公开号:
RU0002589056C2
申请日:
2009.11.04
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry, namely to heterocyclic compound of formula (I), as well as to its pharmaceutically acceptable salt and enantiomer, where R1 is a hydrogen atom, phenyl, linear saturated hydrocarbon chain containing 1-5 carbon atoms, cycloalkyl containing 5-6 carbon atoms, or straight saturated hydrocarbon chain containing 1-4 carbon atoms, substituted cycloalkyl containing 3 carbon atoms; R2 is hydrogen atom, hydroxyl, linear saturated hydrocarbon chain containing 1-5 carbon atoms, straight saturated hydrocarbon chain containing 1-4 carbon atoms, substituted cycloalkyl containing 3-7 carbon atoms, oxygen atom, substituted linear saturated hydrocarbon chain containing 1-4 carbon atoms, an oxygen atom, substituted carbonyl, substituted linear saturated hydrocarbon chain containing 1-4 carbon atoms, carbonyl, substituted linear saturated hydrocarbon chain containing 1-4 carbon atoms, or cycloalkyl containing 6 carbon atoms, carbonyl, substituted by oxygen atom, substituted linear saturated hydrocarbon chain containing 1-4 carbon atoms, Carbonyl, substituted monoalcylamino, alkyl which is linear saturated hydrocarbon chain containing 1 carbon atom, carboxyl group, cyano group or amino group, bisubstituted phenyl or linear hydrocarbon chain containing 1-4 carbon atoms; R3 is linear saturated hydrocarbon chain containing 1 carbon atom, substituted phenyl, possibly substituted with one or two groups, selected from halogen and oxygen, substituted linear saturated hydrocarbon chain containing 1 carbon atom; R4 is linear saturated hydrocarbon chain containing 1-4 carbon atoms, substituted imidazole, unsubstituted or substituted linear saturated hydrocarbon chain containing 1 carbon atom; R5 represents hydrogen atom or linear hydrocarbon chain containing 1-4 carbon atoms; X represents oxygen atom or sulphur atom; n, m equals to 1 or 2. Invention also relates to use of formula (I), pharmaceutical and cosmetic compositions based
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