The present invention concerns a fastener system comprising a cranial plug (160) and a strip fastener (20, 30, 270, 280, 300) for reattaching a skull flap (2) removed from a skull (1) during brain surgery and for closing at least one burr hole or cranial perforation made in the skull (1) to facilitate cutting out a skull flap (2). The cranial plug (160) comprises a flange (162) and at least one extension (163) projecting downwardly and away from a lower surface of the cranial plug (160). The strip fastener (20, 30) comprises a flexible strip (21, 31) having sufficient flexibility to be formed lengthwise around the perimeter (5) of the skull flap (2). The flexible strip (21, 31, 51) has brackets (32) with tabs spaced along the length of the strip, wherein at least one tab extending in a direction opposite to at least one other tab. At least one tab (22, 274, 284) is adapted to be disposed over and adjacent to the skull flap (2) and at least one other tab (24, 275, 285) is adapted to be disposed over and adjacent to the skull (2) when the strip is positioned alongside the bone edge surface of the skull flap (2). The tabs are structured to be attached to the skull flap (2) and to the skull (1) with attachment means.
