Tu, Chi,Hou, Duanjie,Gschwend, Heinz W.,Fu, Jian-Min,Holladay, Mark W.,Abreo, Melwyn,Winther, Michael D.,Chafeev, Mikhail,Chakka, Nagasree,Kamboj, Rajender,Sun, Sengen,Sviridov, Serguei,Sun, Shaoyi,Li
申请号：
AU2010227003
公开号：
AU2010227003B2
申请日:
2010.10.06
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2010227003B220120614.pdf#####C- NRPOnbl DCC DA R 22035 .1 DOC-610/1211191 ABSTRACT Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a 5 mammal in need thereof a compound of formula (la): R4 R5 6a R6 R7 R R 7a R2 -W N N-V-R (1a) N=N R 8a R9a R9 R8 where x, y, W, V, R2 , R3 , R4, R , R , R6a, R , R a, R8 , R8a, R9 and Rea are defined herein. Pharmaceutical compositions comprising the compounds of formula (1) are also 10 disclosed.
