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Polypeptide constructs including VHH directed against EGFR for intracellular delivery
专利权人:
Paul M. P. Van Bergen En Henegouwen;Karen Silence;Mark Vaeck
发明人:
Karen Silence,Mark Vaeck,Paul M. P. Van Bergen En Henegouwen
申请号:
US12487684
公开号:
US09243065B2
申请日:
2009.06.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further relates to a method for delivering therapeutic molecules to the interior of cells. The invention further relates to polypeptide constructs including VHH directed against EGFR.
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