Kim, Hyun Kee,Chung, Junho,Kim, Min Soo,Yoon, Soo Min
申请号：
AU2013232855
公开号：
AU2013232855B2
申请日:
2013.03.15
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease.
