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5-substituted benzoxazines
专利权人:
F. Hoffmann-La Roche AG
发明人:
Kolczewski, Sabine,Roche, Olivier,Steward, Lucinda,Wichmann, Juergen,Woltering, Thomas
申请号:
AU2009289307
公开号:
AU2009289307B2
申请日:
2009.08.28
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention is concerned with 5-substituted benzoxazine derivatives of formula (I), wherein X, R and R are as described herein, as well as their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are 5-HT receptor antagonists, useful in the prevention and/or treatment of depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, dementia, disorders of eating behaviors, sexual dysfunction, sleep disorders, abuse of drugs, motor disorders such as Parkinson's disease, psychiatric disorders or gastrointestinal disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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