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Energy-providing bone-repair degradable porous scaffold, preparation method thereof, and application thereof
专利权人:
HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人:
Shengmin Zhang,Mingle Cai,Haoming Liu
申请号:
US15130361
公开号:
US09855366B2
申请日:
2016.04.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention discloses an energy-providing bone-repair degradable porous scaffold, a preparation method thereof, and an application thereof. The invention obtains an energy-based biomaterial solution by compositing gelatin, a polyatomic acid and derivatives thereof, a dibasic alcohol and derivatives thereof, and a tribasic alcohol and derivatives thereof in a chemical cross-linking manner by using diisocyanate, and further obtains a porous scaffold through a drying method. The porous scaffold can avoid the problem of an acidic microenvironment caused by in vivo implantation of the existing biomaterial and keep the activity of an osteoblast cell, thereby improving the rate of repairing the damaged bone tissue with the energy-based biomaterial. The porous scaffold of the invention can be used as a filling material for bone repair in a surgical operation.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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