Technologies are generally described for detection of foot edema through in-shoe pressure sensors and analysis of detected pressure values. Multiple pressure sensors may be employed in contact with a foot. The pressure sensors may detect pressure generated on a surface of the foot by fluid accumulation within cells of the foot. A change in pressure may be monitored by analyzing pressure values received from the pressure sensors. In some embodiments, a pressure rebound curve may be determined while monitoring the change in the pressure. A comparison between a newly acquired pressure rebound curve and an established-normal pressure rebound curve corresponding to a healthy foot may be made. If the pressure rebound curve is determined to indicate a slower change (rebound) in detected pressure than a change in pressure indicated by the normal pressure rebound curve, the presence of foot edema may be inferred.