GRAY, JEFFREY, LYLE,AMARASIGHE, KANDE,CLARK, CYNTHIA, MONESA,MAIER, MATHEW, BRIAN,NICHOLS, RYAN
申请号：
NZ57440607
公开号：
NZ574406A
申请日:
2007.06.27
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is a compound having the formula (I) e.g (S)-{ 4-[2-(S)-(4-Ethylthiazol-2-yl)-2-(2-phenylacetylamido)ethyl]phenyl} -sulfamic acid wherein R and Z are defined in the specification or a pharmaceutically acceptable salt thereof for treating a disease chosen from diabetic retinopathy, macular degeneration, cancer, sickle cell anemia, sarcoid, syphilis, pseudoxanthoma elasticum, Pagets disease, vein occlusion, artery occlusion, carotid obstructive disease, chronic uveitis/vitritis, mycobacterial infections, Lymes disease, systemic lupus erythematosis, retinopathy of prematurity, Bales disease, Behcets disease, infections causing a retinitis or choroiditis, presumed ocular histoplasmosis, Bests disease, myopia, optic pits, Stargardts disease, pars planitis, chronic retinal detachment, hyperviscosity syndrome, toxoplasmosis, trauma and post-laser complications, diseases associated with rubeosis, and proliferative vitreoretinopathy, Crohns disease and ulcerative colitis, psoriasis, sarcoidosis, rheumatoid arthritis, hemangiomas, Osler-Weber-Rendu disease, or hereditary hemorrhagic telangiectasia, solid or blood borne tumors and acquired immune deficiency syndrome, skeletal muscle and myocardial ischemia, stroke, coronary artery disease, peripheral vascular disease, coronary artery disease.
