BENNETT, MICHAEL JOHN,BETANCORT, JUAN MANUEL,BOLOOR, AMOGH,KALDOR, STEPHEN W.,STAFFORD, JEFFREY ALAN,VEAL, JAMES MARVIN
申请号：
CA2927567
公开号：
CA2927567A1
申请日:
2014.10.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.
