Use of L-2-thiohistidine or its salt, ester or acid group, in a cosmetic composition or in the preparation of the cosmetic composition and as depigmenting agent, is claimed. An independent claim is included for a process for cosmetic caring to reduce or suppress pigment spots of the skin and/or for clearing the complexion, comprising applying the cosmetic composition on an affected area of skin, containing the L-2-thiohistidine.