Implantable materials for use with end effectors like surgical stapling devices, and methods associated with the operation of such end effectors, are provided. In one exemplary embodiment, a staple cartridge assembly includes a cartridge body and a hybrid adjunct material associated therewith. The hybrid adjunct material can include one or more biologic materials, such as a biologic tissue membrane, and one or more synthetic materials, such as a synthetic absorbable polymer. The synthetic absorbable polymer can be associated with the membrane such that the polymer provides structural integrity to the membrane so that the membrane can be securely coupled to the cartridge body. Both the membrane and the polymer can be configured to be securely attached to the tissue by staples of the cartridge body. Other implants, devices, and methods for surgical stapling are also provided.
