ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ФАРМИНТЕРПРАЙСЕЗ" (RU)
发明人:
Небольсин Владимир Евгеньевич (RU),Кромова Татьяна Александровна (RU),Желтухина Галина Александровна (RU)
申请号：
RU2013116822/04
公开号：
RU2013116822A
申请日:
2013.04.12
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. Derivatives of dicarboxylic acid bisamides of the general formula I: in which R is a 5-membered unsaturated heterocyclic group containing from 1 to 2 heteroatoms selected from N and / or S, optionally fused to a 6-membered unsaturated cyclic group； R is a group - C (O) -R-C (O) -, where R is a group - (CH) -, optionally substituted with one or two C-C1-6alkyls, or phenyl, n is an integer from 0 to 4； or their pharmaceutically acceptable salts provided that the compound is not a compound in otor: R represents and R represents a group —C (O) - (CH) —C (O) -； or a compound in which R is and R is a group —C (O) - (CH) —C (O) -. 2. The compound according to claim 1, where R is a group selected from: R is a group selected from —C (O) - (CH) —C (O) -, —C (O) - (CH) —C (O) - , -C (O) - (CH) -C (O) -, -C (O) - (CH) -C (O) -, -C (O) - (CH) -C (O) -, - C (O) -CH-CH (CH) -CH-C (O) -, -C (O) -CH-C (CH) -CH-C (O) -, or a group ,,. 3. Derivatives of dicarboxylic acid bisamides of general formula I: wherein R is a 5-membered unsaturated heterocyclic group containing 1 to 2 heteroatoms selected from N and / or S, optionally fused to a 6-membered unsaturated cyclic group； R is an -C group ( O) -R-C (O) -, where R is a group - (CH) -, optionally substituted with one or two C-Calkyls, or phenyl, n is an integer from 0 to 4； or their pharmaceutically acceptable salts having ability to chelate metal ions. 4. Derivatives of dicarboxylic acid bisamides according to claim 3, capable of chelating Zn, Cu, Fe, Mg, Ca, 5 ions. A medicine for the prevention and / or treatment of viral diseases1. Производные бисамидов дикарбоновых кислот общей формулы I:,в которойRпредставляет собой 5-членную ненасыщенную гетероциклическую группу, содержащую от 1 до 2 гетероатомов, выбранных из N и/или S, необязательно конденсированную с 6-членной ненасыщенной циклической группой；Rпредставляет собой группу -С(О)-R-С(О)-, где Rпредставляет собой группу -(CH)-, необязательно замещенную одним или двумя C-Салкилам
