The present invention provides an FTD and TPI-containing oral pharmaceutical composition which can be orally administered and is stable even under high humidity conditions. An oral pharmaceutical composition comprising α,α,α-trifluorothymidine and 5-chloro-6-(2-iminopyrrolidine-1-yl) methyl-2, 4(1H, 3H)-pyrimidine dione hydrochloride as an active ingredient； and being substantially free of an additive comprising a metal salt.
