GUTMAN, ARIE L.,RUKHMAN, IGOR,TISHIN, BORIS,ETINGER, MARINA M.,FEDOTEV, IRINA M.,PERTSIKOV, BORIS M.,KHANOLKAR, RAM,NISNEVICH, GENNADY A.
申请号：
DK10179360
公开号：
DK2289509T3
申请日:
2005.11.18
申请国别(地区):
DK
年份:
2015
代理人:
摘要：
Methods for making trans-(-)-” 9 -tetrahydrocannabinol and trans-(+)-” 9 -tetrahydrocannabinol are disclosed herein. In one embodiment, a trans-(-)-” 9 -tetrahydrocannabinol composition is prepared by allowing a composition comprising (±)-” 9 -tetrahydrocannabinol to separate on a chiral stationary phase to provide a trans-(-)-” 9 -tetrahydrocannabinol composition comprising at least about 99% by weight of trans-(-)-” 9 -tetrahydrocannabinol based on the total amount of trans-(-)-” 9 -tetrahydrocannabinol and trans-(+)-” 9 -tetrahydrocannabinol. The invention also relates to methods for treating or preventing a condition such as pain comprising administering to a patient in need thereof an effective amount of a trans-(-)-” 9 -tetrahydrocannabinol having a purity of at least about 98% based on the total weight of cannabinoids.
