ОСТИН, Эндрю (GB),ЛИДБИТЕР, Пол (GB),ДОББ, Рой (GB)
申请号：
RU2019107481
公开号：
RU2019107481A
申请日:
2017.08.17
申请国别(地区):
RU
年份:
2020
代理人:
摘要：
A product for monitoring the condition of a wound comprises: (a) a sample application zone； (b) a reaction zone downstream of the sample application zone comprising protease- sensitive polymers； (c) coloured particles； and (d) a viewing zone downstream of the sample application zone and reaction zone. The sample application zone transmits fluid towards the viewing zone. Cleavage of the polymers by protease activity present in applied wound fluid results in carriage of the coloured particles with the wound fluid to the viewing zone thereby providing a visual indication of protease activity in the viewing zone. A product for monitoring the condition of a wound comprises a matrix that absorbs wound fluid. The matrix comprises cross-linked and protease-sensitive polymers forming a reaction zone on/in the matrix, and, coloured particles. The arrangement of the polymers and coloured particles is such that cleavage of the polymers by protease activity present in the wound fluid results in transport of the coloured particles along/through the matrix to provide a visual indication of protease activity in the wound fluid. Companion products, uses, kits and methods of monitoring the condition of a wound are also provided.
