Systems and methods for milling saw blade tooth profiles and saw blades with milled tooth profiles are disclosed herein. The systems include blade milling systems that include a milling head, a blade support structure, a blade advance structure, and a control system. The methods include supporting a saw blade, advancing the saw blade, and machining a finished tooth profile in a working portion of the saw blade with an end mill. In some embodiments, the machining may include operatively translating the end mill relative to the saw blade with a milling head and within a plane that is at least substantially perpendicular to an end mill rotational axis. In some embodiments, the machining may include dry-machining the finished tooth profile in the working portion of the saw blade in a single pass. The saw blades include a plurality of teeth and may include at least one relief region.