Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors

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专利权人:

Domain Therapeutics

发明人:

Mayer, Stanislas,Schann, Stephan

申请号：

AU2013265326

公开号：

AU2013265326A1

申请日:

2013.05.21

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention relates to the pyrazoloquinazolinone and pyrroloquinazolinone derivatives of the general formula (I), as well as pharmaceutical compositions containing them, and their use in the treatment and/or prophylaxis of conditions associated with altered glutamatergic signalling and/or functions, and/or conditions which can be affected by alteration of glutamate level or signalling in mammals, in particular their use in the treatment and/or prophylaxis of acute and chronic neurological and/or psychiatric disorders.

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