Lee, Allen J.,Lee, Jason J.,Lu, David M.,Lee, Ruey-Min
申请号:
AU2014360503
公开号:
AU2014360503A1
申请日:
2014.12.03
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The methods, compositions, and kits of the invention are related to the discovery that lestaurtinib reduces levels and pathway activity of an SPOP substrate. Accordingly, described herein are methods and compositions for the use of lestaurtinib in downregulating one or more SPOP substrates or signaling pathway activities thereof in a subject in need thereof.