FIELD: chemistry.SUBSTANCE: invention relates to novel compounds of general formula 1 or pharmaceutically acceptable salts thereof, which posses PARP (poly(ADP-ribose)polymerase) inhibitor properties. Compounds can be used for prevention or therapy of posterior eye diseases. In formula (1) R1 is a halogen atom R2 and R3 represent a hydrogen atom R4 and R5 represent a hydrogen atom or a deuterium atom, or R4 and R5 can form an oxo group Ra is a hydrogen atom or lower alkyl group, and Rb is a phenyl group or lower alkyl group, substituted with di-(lower alkyl) amino group, or 5-6-member heterocyclic group containing 1-2 heteroatoms in ring, selected from nitrogen atoms or nitrogen atom and an oxygen atom or a phenyl group, or 6-member nitrogen-containing heteroaryl group Ra and Rb can be bonded with each other to form a 5-7-member nitrogen-containing heterocyclic ring, which can contain an additional nitrogen atom, optionally condensed with a benzene ring and optionally substituted with a group, selected from lower alkyl group, lower haloalkyl group, lower cycloalkyl group, lower cycloalkylcarbonyl group, lower alkoxycarbonyl group, low-cycloalkyl-lower alkyl group, di-(lower alkyl) amino group, di-(lower alkyl) amino-lower alkoxy group phenyl group or phenyl-lower alkyl group, in each of which phenyl group can be substituted with 1–2 halogen atoms, hydroxy group, lower alkyl group, lower haloalkyl group, lower alkoxy group, C1-C2alkylenedioxy group 5-6-member heterocyclic group, containing 1–2 heteroatoms in ring, selected from nitrogen atom, oxygen atom and sulphur atom, and/or nitrogen atom and oxygen atom, optionally substituted with a halogen atom and optionally condensed with a benzene ring or pyridine ring ring A is a benzene ring or thiophenyl ring and m is 0 or 1.EFFECT: obtaining novel compounds.12 cl, 61 tbl, 7 exИзобретение относится к новым соединениям общей формулы 1 или их фармацевтически приемлемым солям, которые обладают свойствами ингибитора PARP (п
