ANTICORPS ANTI-GPR-9-6 ET ANTI-TECK ET PROCEDES D'IDENTIFICATION DE MODULATEURS DE FONCTIONS DE GPR-9-6 ET DE TECK

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专利权人:

MILLENNIUM PHARMACEUTICALS; INC.

发明人:

ANDREW, DAVID P.,ZABEL, BRIAN A.,PONATH, PAUL D.

申请号：

CA2365230

公开号：

CA2365230C

申请日:

2000.03.10

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The invention relates to an antibody or antigen-binding fragment thereof whichbinds to the CC chemokine receptor GPR-9-6 and blocks the binding of a ligand(e.g, TECK) to the receptor. The invention also relates to a method ofidentifying agents (molecules, compounds) which can bind to GPR-9-6 andinhibit the binding of a ligand (e.g., TECK) and/or modulate a function of GPR-9-6. The invention further relates to a method of modulating a function of GPR-9-6, and to the use of the antibodies, antigen-binding fragments and agentsidentified by the method of the invention in research, therapeutic,prophylactic and diagnostic methods.

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中国工程科技知识中心

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http://www.ckcest.cn/home/