PHARMACEUTICAL COMBINATION OF 5-FLUOROURACIL AND DERIVATE OF 1,4-DIHYDROPYRIDINE AND ITS USE IN THE TREATMENT OF CANCER

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专利权人:

Gunars Duburs

发明人:

Gunars Duburs,Egils Bisenieks,Irina Sestakova,Ivars Kalvinsh,Brigita Vigante,Janis Uldrikis,Ilona Domraceva,Elina Jascenko,Janis Poikans,Imanta Bruvere,Ilmars Stonans

申请号：

US13138614

公开号：

US20120022088A1

申请日:

2010.03.11

申请国别(地区):

US

年份:

2012

代理人:

摘要：

New compounds of 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester type having general formula Iwherein R is a lower alkyl group, which is methyl or ethylR1 and R2 is sodium carboxylate-methyl ester, having synergistic cytotoxic effect combined with 5-fluorouracil.

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