Alan Smith;Frank Tagliaferri;Mirek Baudys;Gaurav Tolia;David Enscore
发明人:
Frank Tagliaferri,Alan Smith,David Enscore,Gaurav Tolia,Mirek Baudys
申请号:
US12893477
公开号:
US09498609B2
申请日:
2010.09.29
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are a patch, system, and method for delivery of a permeant composition into a subject via at least one formed pathway through a biological membrane of the subject. The patch comprises a matrix, at least one hydrophilic permeant disposed within the matrix, wherein at least a portion of the permeant can dissolve in biological moisture received from the subject, and at least one permeability enhancer disposed within the matrix. Also disclosed are systems and methods for delivery of a permeant composition into a subject via at least one formed pathway through a skin layer of the subject.