Eun Kyung LEE,Myeong Jin GOH,Hyun Jung CHOI,Eun Gyung CHO,Tae Ryong LEE
申请号:
US15521570
公开号:
US20170304175A1
申请日:
2015.11.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure discloses a novel use of genistein, epigallocatechin gallate (EGCG), derivatives thereof, isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof and solvates thereof. A composition containing genistein, epigallocatechin gallate, derivatives thereof isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof or solvates thereof reduces the expression of factors related to increase of melanin producing ability, reduces the expression of senescence marker proteins and regulates the expression of enzymes involved in melanin production, and thus may have an effect of rejuvenating cells including melanocytes.