COMBINING SILDENAFIL WITH CAFFEINE IN AN ORAL DISINTEGRATING DOSAGE FORM

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专利权人:

发明人:

JASTI BHASHARA RAO,SA ABDEL HALEM,MOHAMMED EL NABARAWI,KI EL RAFAAI

申请号：

IN11211/DELNP/2015

公开号：

IN2015DN11211A

申请日:

2015.12.08

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

Pharmaceutical compositions and formulations are provided herein comprising a phosphodiesterase type inhibitor such as sildenafil citrate and an adenosine receptor (A1 A2A A2B and A3 receptors) antagonist such as caffeine for (i) treating erectile dysfunction while (ii) inhibiting the lower of the blood pressure (iii) increasing the bioavailability of the compositions and (iv) reducing the Tmax in the subject. Methods of making and administering oral disintegrating tablets are also provided.

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中国工程科技知识中心

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