Richard R. Anderson,Walfre Franco,Joel N. Jimenez-Lozano,William A. Farinelli
申请号:
US14421592
公开号:
US20150216545A1
申请日:
2013.08.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Exemplary methods and devices can be provided for harvesting a plurality of small tissue pieces, e.g., having widths less than about 1 mm or 0.5 mm, using one or more hollow needles. A fluid can be flowed through a conduit past the proximal ends of the needles to facilitate removal of the tissue pieces from the needle lumens, and can maintain the tissue pieces in a controlled and protective liquid environment. A filter can be used to extract and collect the tissue pieces from the liquid, or the tissue pieces can be deposited directly onto a porous dressing. Such tissue pieces can be used as microscopic grafts, which can be applied directly to a wound site or provided on a substrate or dressing, or stored for later use. Such microscopic grafts can promote tissue regrowth and wound healing, or can be applied to a scaffold to grow new tissue.