PROBLEM TO BE SOLVED: To provide a composition containing a nanobubble containing hydrogen, oxygen, and nitrogen, and to provide an application thereof.SOLUTION: The invention provides a composition containing, as an active ingredient, a nanobubble with a particle diameter of 30 micrometers or less containing 0.45-0.55 ppm of hydrogen, 10-12.5 ppm of oxygen, and 7-8 ppm of nitrogen； a mitochondrial activation composition, a cell growth accelerator, and a cell preservation liquid or cryopreservation liquid containing the composition； a method for using the composition, the agent, or the liquid, and food and drink or raw materials for food and drink produced using the composition.SELECTED DRAWING: Figure 1【課題】水素、酸素、窒素を含有するナノバブルを含有する組成物とその用途の提供。【解決手段】水素０．４５～０．５５ｐｐｍ、酸素１０～１２．５ｐｐｍ、窒素７～８ｐｐｍ含有する、粒径３０マイクロメートル以下のナノバブルを有効成分として含有する組成物、及び前記組成物を含有する、ミトコンドリア活性化組成物、細胞増殖促進剤、細胞保存液又は凍結保存液、前記組成物、剤又は液の使用方法、並びに前記組成物を使用して製造した飲食物又は飲食物原料。【選択図】図１
