Canning, Peter Connor,Knudsen, Nickolas,Skidmore, Lillian
申请号:
AU2017280958
公开号:
AU2017280958A1
申请日:
2017.06.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Disclosed herein are porcine interferon alpha variants (pINF-α) comprising a synthetic amino acid at select locations in pINF-α and a one or two amino acid insertion in the N-terminus after removal of the signal peptide. The pINF-α variants can further be pegylated. Methods of making and administering these compounds to treat virus infections in pigs and formulations comprising the variants are also provided.