Georg Achleitner,Eva-Maria Hoiser,Laura Pickersgill
申请号:
US13093608
公开号:
US08765149B2
申请日:
2011.04.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Described are sterile, ready-to-use, pharmaceutical oil-in-water emulsion compositions for parenteral administration comprising:0.015 to 0.5% wt/vol progesterone;0.5 to 10% wt/vol oil, wherein the oil comprises at least 85% wt./wt. triglyceride;0.0425 to 4.1% wt/vol phospholipid;80-99.4% wt/vol aqueous medium;wherein the composition has an osmolality in the range of 200-1000 mOsm/kg.Also described are methods of making such compositions and method of using such compositions in therapeutic or prophylactic treatment, such as treatments comprising intravenous administration of the pharmaceutical composition.