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Avian cells for improved virus production
专利权人:
ザ パーブライト インスティテュート
发明人:
ファイフ, マーク,ギブソン, マーク
申请号:
JP2016517675
公开号:
JP6599316B2
申请日:
2014.06.03
申请国别(地区):
JP
年份:
2019
代理人:
摘要:
The present invention provides an avian cell in which the expression or activity of one or more of the following genes, or a homologue thereof: Chicken IFITM1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3) is reduced. The invention also provides methods for passaging viruses in avian cells, embryos and/or avian cell lines which have reduced expression of one or more IFITM genes and methods which involve investigating the sequence of one or more of the following genes, or a homologue thereof: Chicken IFITM1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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