SK CHEMICALS CO., LTD.; LTD.;SK CHEMICALS CO.;에스케이케미칼 주식회사
发明人:
SHIN, DongChul,신동철,SHIN, Ho Chul,신호철,JANG, Woo-Je,장우제,KIM, Gwan-Young,김관영,YOO, Jong-Su,유종수,YOO, Hunseung,유헌승
申请号：
KRKR2016/002254
公开号：
WO2016/144071A2
申请日:
2016.03.07
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a fast release pharmaceutical formulation comprising non-aqueous hydrophilic bound granules containing rivaroxaban, the granules being coated, and a method for preparing the same. The present invention is capable of providing a fast release pharmaceutical formulation which guarantees high bioavailability of rivaroxaban and is excellent as a coated pharmaceutical formulation, and a method for preparing the same.La présente invention concerne une formulation pharmaceutique à libération rapide comprenant des granulés liés hydrophiles non-aqueux contenant du rivaroxaban, les granulés étant enrobés, et son procédé de préparation. La présente invention est capable de fournir une formulation pharmaceutique à libération rapide, qui garantit une biodisponibilité élevée de rivaroxaban et est excellente comme formulation pharmaceutique revêtue, et son procédé de préparation.본 발명은 리바록사반 함유 비수성 친수화 결합 과립을 포함하고 상기 과립은 코팅된, 속방출성 약학제제 및 이의 제조방법에 관한 것이다. 본 발명에 따르면, 리바록사반의 높은 생체이용율을 확보하는 동시에, 코팅된 약학제제로서의 우수성을 보유한 속방출성 약학제제 및 이의 제조방법을 제공할 수 있다.
