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APPARATUS AND METHOD FOR MANUFACTURING MICRONEEDLE PATCH, AND MICRONEEDLE PATCH MANUFACTURED BY SAME
专利权人:
发明人:
Han Wook PARK
申请号:
US15769107
公开号:
US20180311486A1
申请日:
2016.08.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a microneedle patch of which continuous production is possible by a rotary method and in which a front end thereof is composed of hyaluronic acid, and a manufacturing method and a manufacturing device suitable for continuous production of the same.The microneedle patch according to the present invention is one of which a myriad of needle-shaped parts composed of hyaluronic acid are pressed to be attached to a surface of an adhesive layer 4 laminated on a substrate 2, one of which part of the hyaluronic acid layer 8 which is coated on the surface of the adhesive layer 4 is formed into a needle-shaped part 6 so as to be pressed to be attached thereto, or one of which the hyaluronic acid layer 8 is laminated on the substrate 2 composed of a thin film and then pressed so as to be arranged into a myriad of needle-shaped parts 6. The microneedle patch is continuously manufactured by a method in which the adhesive layer 4 is coated on a substrate 2 by primary gravure coating followed by drying, and then an aqueous hyaluronic acid solution is coated by secondary gravure coating and pressed so as to form a needle-shaped part 6, or in which the hyaluronic acid layer 8 is coated on the substrate 2 and pressed so that part of the hyaluronic acid layer 8 is formed into a needle-shaped part 6. A manufacturing device which includes a first coating part 20 that coats the substrate 2 with an adhesive layer 4 or a hyaluronic acid layer 8, and a second coating part 30 including needle-forming rollers 33 and pressure rollers 35 that press the first drying part 26 and the substrate 2 so as to form a needle-shaped part 6, by a rotary method, is also included.
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