Anti-n3pglu amyloid beta peptide antibodies and uses thereof

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专利权人:

ELI LILLY AND COMPANY

发明人:

LU JIRONG,TANG YING,DEMATTOS RONALD BRADLEY

申请号：

NZ60609511

公开号：

NZ606095A

申请日:

2011.08.09

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Discloses anti-N3pGlu A&bgr antibodies or antigen-binding fragments thereof and related compositions and therapeutic use of said compositions for treating Alzheimer&rsquos disease, Down&rsquos syndrome and cerebral amyloid angiopathy. The antibodies claimed comprise: LCDR1 of KS**SLLYSR*KTYLN, LCDR2 of AVSKL*S, LCDR3 of VQGTHYPFT and HCDR1 of GY*FT*YYIN, HCDR2 of WINPGSGNTKYNEKFKG, HCDR3 of EG*TVY.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/