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RAPID ESTABLISHMENT AND/OR TERMINATION OF SUBSTANTIAL STEADY-STATE DRUG DELIVERY
专利权人:
Intarcia Therapeutics; Inc.
发明人:
Alessi, Thomas R.,Luskey, Kenneth L.
申请号:
AU2014280920
公开号:
AU2014280920A1
申请日:
2014.12.23
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2014280920A120150122.pdf#####ABSTRACT The present invention is directed to treatment methods for a disease or condition, in a subject in need of such treatment, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method typically includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is typically achieved within about 7 days or less after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using incretin mimetics.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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