BLOOM, LAIRD,GILL, DAVINDER,VUGMEYSTER, YULIA,YOUNG, DEBORAH A.,LOWE, DAVID,VALGE-ARCHER, VIIA
申请号：
MYPI 2010005509
公开号：
MY149448A
申请日:
2009.05.26
申请国别(地区):
MY
年份:
2013
代理人:
摘要：
THE PRESENT INVENTION PROVIDES BINDING PROTEINS AND ANTIGEN-BINDING FRAGMENTS THEREOF THAT SPECIFICALLY BIND TO THE HUMAN INTERLEUKIN-21 RECEPTOR (IL-21 R). THE BINDING PROTEINS CAN ACT AS, E.G., ANTAGONISTS OF IL-21R ACTIVITY, THEREBY MODULATING IMMUNE RESPONSES IN GENERAL, AND THOSE MEDIATED BY IL-21R IN PARTICULAR. THE DISCLOSED COMPOSITIONS AND METHODS MAY BE USED, E.G., IN DIAGNOSING AND/OR TREATING IL-21R-ASSOCIATED DISORDERS, E.G., INFLAMMATORY DISORDERS, AUTOIMMUNE DISEASES, ALLERGIES, TRANSPLANT REJECTION, CANCER, AND OTHER IMMUNE SYSTEM DISORDERS.
