C. Jeffrey Brinker,David S. Peabody,Walker Kip Wharton,Bryce Chackerian,Carlee Erin Ashley,Cheryl L. Willman,Eric C. Carnes,Katherine Epler,Robert Eric Castillo
申请号：
US14369741
公开号：
US20150010475A1
申请日:
2012.12.31
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to the use of which are attached or anchored phospholipid biolayers further modified by CRLF-2 and CD 19 binding peptides which may be used for delivering pharmaceutical cargos, to cells expressing CRLF-2 and CD 19, thereby treating cancer, in particular, acute lymphoblastic leukemia (ALL), including (B-precursor acute lymphoblastic leukemia (B-ALL). Novel CRLF-2 binding peptides and CLRF-2 and CD19-binding viral-like particles (VLPs) useful in the treatment of cancer, including ALL are also provided.
