Saurabh Saha,Dean Welsch,Gary DeCrescenzo,Jeffrey James Roix
申请号:
US15105871
公开号:
US20160367539A1
申请日:
2014.12.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides, inter alia, methods, kits, and pharmaceutical compositions for treating or ameliorating the effects of a cancer in a subject in need thereof. The method includes administering to the subject an effective amount of (i) a first anti-cancer agent, which is BVD 523 or a pharmaceutically acceptable salt thereof and (ii) a second anti-cancer agent, which is a type 2 MEK inhibitor, or other MEK inhibitors, or pharmaceutically acceptable salts thereof, to treat or ameliorate the effects of the cancer. Additional methods for effecting cancer cell death are also provided.