Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human Flt3L or GM-CSF for cancer immunotherapy
Deng, Liang,Shuman, Stewart,Wolchok, Jedd,Merghoub, Taha,Wang, Weiyi,Dai, Peihong,Yang, Ning
申请号:
AU2017222686
公开号:
AU2017222686A1
申请日:
2017.02.25
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of poxviruses, specifically the replication competent attenuated vaccinia virus with deletion of thymidine kinase (VC-TK