Institut Pasteur;Centre National de la Recherche Scientifique
发明人:
申请号：
EP04741016.2
公开号：
EP1633776B1
申请日:
2004.06.18
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The invention relates to modified Bordetella adenylate cyclase toxins which are deficient for CD11b/CD18 binding and to their use in the preparation of pharmaceutical composition for the treatment of whooping cough and/or for the protection against Bordetella infection. The invention also relates to specific fragments of Bordetella adenylate cyclase comprising the CD11b/CD18 interaction domain and their use, especially for targeting a molecule of interest to CD11b expressing cells.
