ALMASSY, Robert,SHOWALTER, Richard E.,THOMSON, James A.,SISSON, Wes,SHIA, Wei-Jong,CHEN, Li-Chang,LEE, Yang
申请号：
HK16102073.8
公开号：
HK1214139A
申请日:
2016.02.24
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.
