用於治療胰臟癌的方法农业专利-农业学术服务平台

专利权人:: PTC THERAPEUTICS, INC.;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

发明人:: WEETALL, MARIA L.,韦塔尔　马里亚　Ｌ,韋塔爾　馬里亞　Ｌ,CAO, LIANGXIAN,曹　良弦,DAVIS, THOMAS W.,戴维斯　汤玛士　Ｗ,戴維斯　湯瑪士　Ｗ,DUMBLE, MELISSA L.,唐宝　莫里沙　Ｌ,唐寶　莫里沙　Ｌ,EBERLE-SINGH, JAIME A.,安博尔　辛格　贾姆　Ａ,安博爾　辛格　賈姆　Ａ,OLIVE, KENNETH P

摘要：: A method for treating pancreatic cancer in a subject in need thereof comprising, administering to the subject an effective amount of a tubulin polymerization inhibitor compound is described herein. More particularly, a method for treating pancreatic ductal adenocarcinoma in a subject in need thereof comprising, administering to the subject an effective amount of a substituted reverse pyrimidine tubulin polymerization inhibitor compound alone or in combination with other chemo-therapeutic agents is described herein.本發明闡述用於治療有需要個體之胰臟癌的方法，其包含向該個體投與有效量之微管蛋白聚合抑制劑化合物。更具體而言，本發明闡述用於治療有需要個體之胰臟導管腺癌的方法，其包含將有效量之經取代之反向嘧啶微管蛋白聚合抑制劑化合物單獨或與其他化學治療劑組合投與給該個體。