Disclosed are systems, devices, materials and method, including a system that includes an energy delivery apparatus to apply energy generated by an energy source to a target area, and a flexible deformable bio-degradable protective material configured to be deformed to define irregular surfaces. The deformable bio-degradable material is also configured to be placed in a location between the target area and another area, to interact with energy not absorbed by the target area to protect the other area, at least partly, from the energy not absorbed by the target area, and further configured to degrade over a period of time when the deformable bio-degradable material is placed substantially permanently proximate the location between the target area and the other area.