Liliana Atanasoska,Robert W. Warner,Michael S. Arney,Jan Weber
申请号：
US11881749
公开号：
US08815273B2
申请日:
2007.07.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
In accordance with an aspect of the invention, implantable or insertable medical devices are provided that comprise (a) a substrate and (b) a porous layer comprising close packed spherical pores disposed over the substrate. The porous layer may also comprise a therapeutic agent. In another aspect, the present invention provides methods of forming implantable or insertable medical devices. These methods comprise forming a predecessor structure that comprises (i) a substrate over which is disposed (ii) an assembly of microspheres. This assembly of microspheres is then used as a template for the formation of a porous layer, which may be subsequently loaded with a therapeutic agent.
